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NUCLEAR RECEPTOR COACTIVATORS
Descriptors Found:
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DeCS
Descriptor
English
:
Nuclear Receptor Coactivators
Descriptor
Spanish
:
Coactivadores de Receptor Nuclear
Descriptor
Portuguese
:
Coativadores de Receptor Nuclear
Tree Number:
D12.644.360.024.314
D12.776.157.057.080
D12.776.476.024.394
D12.776.660.675
D12.776.930.617
Definition
English
:
Proteins
that enhance
gene expression
when associated with ligand bound activated NUCLEAR RECEPTORS. The coactivators may act through an enzymatic process that affects the rate of transcription or the structure of
chromatin
. Alternatively
nuclear receptor coactivators
can function as adaptor
proteins
that bring nuclear receptors into close proximity with transcriptional complexes.
History Note
English
:
2010
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53620
Unique Identifier:
D056918
Occurrence in VHL
:
Similar:
DeCS